Fresh off their FA Cup triumph, Liverpool will travel to the St. Mary’s Stadium for their Premier League 2021-22 matchday 37 fixture against Southampton on Wednesday, May 18. The EPL match kicks off at 12:15 AM IST (Indian Standard Time).

Southampton vs Liverpool Premier League 2021-22 standings

With 40 points from 36 matches, Southampton are currently 15th on the EPL 2021-22 table. The Saints are six points off the relegation zone and are more or less safe from a drop. A single point on Wednesday, meanwhile, ensures Ralph Hasenhüttl’s side stays up for next season. 

Liverpool, meanwhile, will have far more urgency to win Wednesday’s match. Jurgen Klopp’s men are currently second with 86 points from 36 matches - four points behind league leaders Manchester City but with a game in hand. A loss, even a draw, on Wednesday will end their title challenge this season while a win will ensure the EPL 2021-22 title hunt goes down to the final matchday of the season.

Southampton vs Liverpool Premier League 2021-22 odds

  • Dafabet: Southampton 7.00, Liverpool 1.42, Draw 5.40
  • Bet365: Southampton 6.50, Liverpool 1.40, Draw 5.00
  • 10Cric: Southampton 6.67, Liverpool 1.41, Draw 5.25
  • Parimatch: Southampton 7.50, Liverpool 1.40, Draw 5.30

Note: Odds are subject to change. Please visit betting sites to check and confirm the latest odds.

Southampton vs Liverpool head-to-head

Since 1902, Southampton and Liverpool have faced each other 115 times in all competitions. The Merseysiders have won 59 while the Saints have managed just 25 victories. A total of 31 matches have ended in stalemates


When the two met in the Premier League earlier this season at Anfield, Liverpool thumped Southampton 4-0 courtesy goals from Virgil van Dijk, Thiago Alcantara and Diogo Jota (brace). The Reds have, in fact, won eight of their last Premier League meetings against Southampton

The Saints, though, did beat Liverpool 1-0 in their home leg last season.

Southampton vs Liverpool Premier League 2021-22 top picks and players to watch

Southampton:Up against an attacking unit like Liverpool, Southampton will have to defend well if they are to get anything out of the match and key to that will be goalkeeper Fraser Foster. The 34-year-old has just the three clean sheets from 19 Premier League outings this season, but has put on some impressive performances behind a defence which can be termed leaky at best. 

Liverpool: Though a win would help Liverpool extend this season’s title race against City to the final matchday, a victory with a heavy margin over the Saints can help them close down the goal difference with City - which may prove crucial if Liverpool and City end level on points. So expect the Reds to go all out for goals against Liverpool right from the start and the team will invariably depend on their top three- Sadio Mane, Mohamed Salah and Diogo Jota to deliver.

Salah is the EPL’s top scorer this season with 22 goals while both Mane, a former Southampton player, and Jota have netted 15 each.

Southampton vs Liverpool Premier League 2021-22 prediction

Taking into account their recent form, history and current squads, it’s hardly surprising that Liverpool will go into Wednesday’s match as the firm favourites over Southampton. Furthermore, Jurgen Klopp’s charges have that extra motivation to win compared to the Saints, which tilts the odds in their favour even more.